PARTICIPATING LABS

Karthaus, Wouter



The Karthaus lab focuses on understanding the normal biology and cancer biology of steroid hormone regulated organs, such as the prostate, mammary gland and endometrium. We use a multidisciplinary approach, combining organoid cultures, mouse models, genomics and single cell techniques to answer complex biological questions.

Lab website

Key technologies
  • Organoid technology, single cell multiomics, genetic mouse models, genomic engineering
  • • Focus areas
  • Prostate cancer, drug resistance, tumor evolution, organoid technology
Key biological questions
  • What are the drivers on tumor initation, progression and drug resistance in steroid hormone dependent cancers?
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Focus areas